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Migraine IV Cocktail

by Brandon Lang

Thanks to the numerous technological advancements in today’s age, IV therapy has become an easily accessible treatment for many patients. While some use it to help them battle a nasty case of the flu, others turn to it to try and relieve hangover symptoms. With its various possible uses and benefits, more people than ever are interested in trying it out. That’s why this article will focus on explaining the effects and ingredients of a migraine IV cocktail.

By elaborating on each ingredient separately, you’ll have a better understanding of how this treatment works and how it may affect you. Furthermore, you’ll gain insights into the medications commonly used in this treatment and their mechanism of action. Continue reading to discover the migraine cocktail IV ingredients and their benefits!

Source: shutterstock.com / Photo Contributor: Andrey_Popov

What is a Migraine IV Cocktail?

Before elaborating on the cocktail ingredients, you should first understand what migraine IV cocktails are. In simple terms, this type of treatment involves the use of a combination of medicines and vitamins designed to relieve migraine pain through an intravenous route.

The common IV cocktail can contain different types of ingredients. Usually, this includes a saline solution, nutrients, and medications. Even though the IV components may vary depending on the patient’s condition, the professional medical team applying this treatment is the one to determine the right options for you.

The way migraine IV cocktails differ from other types of migraine medication is because they include a combination of ingredients that directly enter your bloodstream. Thus, the main differences between IV fluids and other types of medication are:


  • Better absorption– taking oral medication may lead to loss of the ingredients during the digestion process. While it’s thought that only 50% of orally taken medicine is absorbed, the rates of IV fluids are up to 90%.

  • Accelerated effects– since IVs skip the digestive system, they’re praised for their fast-acting effectiveness and symptom relief.

  • Hydration– besides boosting the body with the needed medication, IV fluids also rehydrate your body, giving it the needed fluids and electrolytes.

Components of the Migraine IV cocktail

After discovering what migraine IV cocktails are, you should also inform yourself about their ingredients. This way, you’ll understand how this treatment affects your body and have a better insight into what benefits you may experience. That being said, here are the common ingredients found in migraine IV cocktails and used by the best mobile IV therapy nurses in AZ:


  • Saline solution

  • Antiemetics

  • NSAIDs

Saline solution

Every IV therapy uses a saline solution as a base to which other ingredients are later added. This combination of water and sodium (salt) is commonly used to provide the patient with much-needed hydration. Since many migraine attacks often include symptoms of vomiting, your body can easily become dehydrated.

Thus, one of the first things that doctors do when a patient enters the ER with a migraine attack is to give them IV fluids to replenish their fluid levels. Even though further studies are required to define the effect saline has in migraine treatment, many doctors believe that fluid replacement is essential for treating acute migraines.

Antiemetics

The second essential ingredient found in migraine IV cocktails is antiemetics or antihistamines. This type of medication is used to combat the symptoms of vomiting that are often present during a migraine headache.

Since migraine attacks may also lead to hypersensitivity to dopamine, antiemetics are useful for their dopamine antagonist properties. Some researchers go as far as to suggest that the application of these medications through IV should be considered as first-line migraine therapy.

When choosing the right migraine cocktail, it’s important to ensure it contains at least some of this medication. For example, the Drip IV Infusion has different kinds of cocktail options with these ingredients, while also offering specific add-ons. The most efficient medicines they feature are Zofran, Pepcid, and Benadryl.

NSAIDs 

NSAIDS, also known as non-steroidal anti-inflammatory drugs, are the last common medicines found in migraine IV cocktails. They’re designed to aid in pain relief, inflammation, and temperature management. Thus, they’re commonly used to treat period pain and headaches.

Since this type of medicine is known to block cyclooxygenase, it also decreases the synthesis of prostaglandins, thought to be involved in the pathophysiology of migraines. Due to their cost-efficiency and availability as over-the-counter medicine, NSAIDs are thought to be the most commonly used therapy to treat this dreadful condition.

When including this medicine in migraine IV cocktails, it may come in different brands or doses. However, one of the most used NSAIDs in IV fluids is the renowned Toradol. Since it has the ability to reduce the hormones causing inflammation and pain, it’s thought to be highly effective in migraine pain relief. 

Source: shutterstock.com / Photo Contributor: azazello photo studio

Supplementary components 

Besides the commonly used medicine, many IV fluids also contain supplementary components. The ones thought to be beneficial for treating migraine headaches are the following:


  • Magnesium

  • Vitamin C

  • Vitamin B

  • Zinc

  • Glutathione

Magnesium

The first commonly used nutrient in migraine IV cocktails is magnesium. Many researchers believe that this ingredient can be efficiently used as migraine treatment in patients who have experienced contraindications from other migraine medicines. Even though no research indicates magnesium deficiency as a cause of this condition, studies suggest that high doses applied through IV fluids can aid in migraine relief.

The reason why this ingredient is used in migraine cocktails is because it affects nerve conduction in the peripheral and central nervous systems. By reducing the excessive stimulation of the brain receptors, this ingredient is thought to not only reduce the severity of the attacks but also minimize their frequency.

Vitamin C

The next important IV compound for migraine treatment is vitamin C. This ingredient is popular due to its antioxidant properties, which protect the body’s cells from free-radical damage. When it comes to a migraine attack, this vitamin may be used to treat the neurogenic inflammation caused by it.

Even though further studies are needed, scientists highlight the importance of taking at least 1000 mg of vitamin C daily to minimize the severity of the attacks. This belief comes from a nonrandomized study where antioxidants like vitamin C were used in combination with vitamin E to improve the migraine outcome. Thus, injecting the needed dose of this ingredient through IV fluids may give your body the relief it’s been looking for.

Vitamin B

Vitamin B is another important element in migraine IV treatment. One study shows that those suffering from frequent migraine attacks usually have lower levels of vitamin B12, linking its deficiency to headaches. 

Another study shows that vitamins B6 and B12 may be potentially used to lower homocysteine levels, which reduces the disability caused by the migraine attack. Alongside vitamin B9, it may reduce the severity of migraine and the frequency of the attacks.

Zinc

Another important ingredient found in this treatment is zinc. Like vitamin B, some researchers believe that a deficiency from this mineral can cause more frequent migraines. Thus, a study was conducted to observe the effects this ingredient had on the control group.

This study revealed that those who took zinc supplements experienced a decrease in the frequency of migraine attacks. Even though further studies are needed, including zinc in migraine IV cocktails may give your body a refreshing boost.

Glutathione

The last important migraine ingredient in the IV cocktail you should know about is glutathione. Since it’s believed that migraines are linked to oxidative stress, it’s important to try and reduce this factor. Thus, scientists researched the effects glutathione had on the frequency and severity of migraine attacks.

This study resulted in a decline in oxidative stress, which directly influenced the migraine. The patients experienced a 50% improvement in both the frequency and severity of the attacks.

Considerations and Limitations

If you’re interested in trying migraine IV cocktails, there are several factors you should consider. First, the application of intravenous fluids should always be done by a professional medical team. Since it involves needle insertion, the area must be cleaned, and the needle needs to be carefully applied with medical-grade gloves.

Furthermore, having a professional medical team by your side will help alleviate any anxiety you may be feeling during the treatment. The designated nurses will guide you through the process and answer any questions you may have. 

However, as with any medical treatment, there are several limitations you should also be aware of. Even though this type of IV therapy may help alleviate the pain associated with migraine headaches, it’s not considered a long-term solution. Thus, if you’re experiencing frequent headaches, it’s recommended to consult with your primary healthcare doctor to discuss the right treatment options. 

Remember that migraines can last up to 72 hours, so experiencing prolonged symptoms may be a sign of another underlying condition. That’s why it’s best to first consult with a medical physician before you start taking IV fluids to decide if they’re the right course of action. 

Source: shutterstock.com / Photo Contributor: fizkes

Conclusion

After discovering the use and ingredients found in a migraine IV cocktail, it’s up to you to decide if this is the right treatment option for you. Just remember that an experienced medical team should always apply this type of treatment to prevent any unwanted complications.

As mentioned, the main ingredients found in migraine IV cocktails are saline, NSAIDs, antiemetics, and supplementary components. While the medicine is used to relieve the pain, the supplementary components may help reduce the frequency of the attacks and give the body an additional boost.

Lastly, besides including the necessary IV compounds to help alleviate migraine pain, this cocktail is not considered a long-term solution. So, contacting your healthcare physician before trying this treatment is always recommended.

Brandon Lang, MSN, RN

Co-founder and Chief Executive Officer

Brandon Lang started his healthcare career working on an ambulance as an EMT at just 19 years old in Los Angeles, CA. He transitioned into a new-grad program in the ICU and then into the ER, ultimately working over 14 years in the ER. Toward the end of his ER tenure, Brandon also worked as a critical care transport (CCT) RN in Southern CA for approximately 2 years while pursuing his dream of becoming a flight nurse and working on a helicopter. He became a flight nurse in 2001 and served communities in AZ and CA in the air medical industry for over 17 years.

Brandon’s “why” in all of this is his relationship with Christ as the foundation in all he does, his amazing wife of over 23 years and their six children. Brandon knows that helping build both Haggai Healthcare and The Drip IV Infusion would not be possible without an amazing group of professionals around him. He is incredibly grateful for a team whose values align believing that if they take great care of their team, the team in turn will take amazing care of the patients and clients to which they have the honor of providing health services.

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